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Drug ReportsAscorbic acid
Ascorbic acid
/ / / / /, Ascor, Berocca Pn, Infuvite, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Moviprep, Mvc, Plenvu, Vitaped (ascorbic acid) is a small molecule pharmaceutical. Ascorbic acid was first approved as M.v.i.-12 lyophilized on 1985-08-08. It is used to treat common cold, methemoglobinemia, penetrating wounds, scurvy, and tyrosinemias in the USA. It is known to target solute carrier family 23 member 2.
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Financial
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5D
1M
3M
6M
YTD
1Y
2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Primary completion date
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Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
nervous system diseasesD009422
cardiovascular diseasesD002318
hemic and lymphatic diseasesD006425
hereditary congenital and neonatal diseases and abnormalitiesD009358
nutritional and metabolic diseasesD009750
wounds and injuriesD014947
Trade Name
FDA
EMA
Ascor
Combinations
Infuvite, Moviprep, Peg, sulfate, chloride, potassium chloride, ascorbate ascorbic acid, Plenvu (discontinued: Berocca pn, M.v.c. 9+, M.v.i., M.v.i. lyophilized, Mvc, Vitaped)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ascorbic acid
+
Polyethylene glycol 3350
+
Potassium chloride
+
Sodium ascorbate
+
Sodium chloride
+
Sodium sulfate
Tradename
Company
Number
Date
Products
PLENVUSalix PharmaceuticalsN-209381 RX2018-05-04
1 products, RLD, RS
MOVIPREPSalix PharmaceuticalsN-021881 RX2006-08-02
1 products, RLD, RS
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin e
Tradename
Company
Number
Date
Products
BEROCCA PNRocheN-006071 DISCN1985-10-10
1 products
Hide discontinued
Alpha-tocopherol acetate
+
Ascorbic acid
+
Biotin
+
Cholecalciferol
+
Cyanocobalamin
+
Dexpanthenol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin k
Tradename
Company
Number
Date
Products
INFUVITE ADULTSandozN-021163 RX2000-05-18
2 products, RLD, RS
Ascorbic acid
+
Biotin
+
Cholecalciferol
+
Cyanocobalamin
+
Dexpanthenol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Tocopherol acetate
+
Vitamin a
+
Vitamin k
Tradename
Company
Number
Date
Products
INFUVITE PEDIATRICSandozN-021265 RX2001-02-21
1 products, RLD, RS
INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE)SandozN-021265 RX2004-01-29
1 products, RLD, RS
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.C. 9+3APP PharmaceuticalsN-018440 DISCN1985-08-08
1 products
M.V.I.-12 ADULTHospiraN-008809 DISCN1985-08-08
2 products
MVC PLUSAllerganN-018439 DISCN1985-08-08
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.I.-12 ADULTHospiraN-008809 DISCN2004-04-22
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.I. PEDIATRICHospiraN-018920 DISCN2000-09-21
1 products, RLD
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Tradename
Company
Number
Date
Products
M.V.I. ADULTHospiraN-021625 DISCN2004-01-30
1 products, RLD
M.V.I. ADULT (PHARMACY BULK PACKAGE)HospiraN-021643 DISCN2004-02-18
1 products, RLD
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pantothenic acid
+
Phytonadione
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Vitamin a palmitate
+
Vitamin e
Tradename
Company
Number
Date
Products
VITAPEDHospiraN-020176 DISCN1993-12-29
1 products
Hide discontinued
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin 5'-phosphate sodium
+
Thiamine
+
Vitamin a
+
Vitamin e
Tradename
Company
Number
Date
Products
M.V.I.-12 LYOPHILIZEDTeligentN-018933 DISCN1985-08-08
1 products
Hide discontinued
Ascorbic acid
Tradename
Company
Number
Date
Products
ASCORMcGuff PharmaceuticalsN-209112 RX2017-10-02
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
acetaminophen, ascorbic acid, chlorpheniramine maleateExport only2024-05-08
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aoao snaili ginseng anti wrinkle creamC2002632024-09-26
aoao snow bieach intensive for face and bodyC2002632024-10-18
aoao whitening creamC2002632024-10-13
aromacura shower filterunapproved drug other2021-01-05
aronamin goldunapproved drug other2018-12-12
Show 253 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
common coldEFO_0007214D003139J00
constipation—D003248K59.0
methemoglobinemia—D008708D74
penetrating wounds—D014950—
tyrosinemias—D020176E70.21
scurvyEFO_1001169D012614E54
hypercholesterolemia—D006937—
hypophosphatemiaHP_0002148D017674—
hypertriglyceridemiaEFO_0004211D015228—
peripheral vascular diseasesEFO_0003875D016491I73.9
Show 27 more
Agency Specific
FDA
EMA
Expiration
Code
ASCORBIC ACID, ASCOR, MCGUFF
2024-10-02ODE-160
Patent Expiration
Patent
Expires
Flag
FDA Information
Ascorbic Acid / Polyethylene Glycol 3350 / Potassium Chloride / Sodium Ascorbate / Sodium Chloride / Sodium Sulfate, Plenvu, Salix
89993132033-09-10DP
93269692033-09-10U-2310
97072972033-09-10DP
100165042033-09-10DP
109187232033-09-10U-2310
95922522032-08-11DPU-2310
106465122032-03-25DP
107801122032-03-09DP
107923062032-03-09DPU-2310
115293682032-03-09DPU-2310
Ascorbic Acid / Polyethylene Glycol 3350 / Potassium Chloride / Sodium Ascorbate / Sodium Chloride / Sodium Sulfate, Moviprep, Salix Pharms
71693812024-09-01DS, DP
76589142024-09-01DS, DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A11: Vitamins
— A11G: Ascorbic acid (vitamin c), incl. combinations
— A11GA: Vitamin c products, plain
— A11GA01: Ascorbic acid
— A11GB: Vitamin c combinations
— A11GB01: Ascorbic acid and calcium
G: Genito urinary system and sex hormones
— G01: Gynecological antiinfectives and antiseptics
— G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
— G01AD: Organic acids, gynecological
— G01AD03: Ascorbic acid
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01X: Other ophthalmologicals in atc
— S01XA: Other ophthalmologicals in atc
— S01XA15: Ascorbic acid
HCPCS
No data
Clinical
Clinical Trials
2213 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HepatitisD006505—K75.91——1—2
Hepatitis aD006506EFO_0007305B151——1—2
Hepatitis cD006526—B19.2———1—1
Chronic hepatitis cD019698EFO_0004220B18.2———1—1
Chronic hepatitisD006521—K73.9———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179———12——3
Colonic neoplasmsD003110—C18——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myelodysplastic syndromesD009190—D46711——420
Myeloid leukemia acuteD015470—C92.0107——318
PreleukemiaD011289——79——317
Multiple myelomaD009101—C90.0711——317
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.921——1417
Myeloid leukemiaD007951—C9298——116
Plasma cell neoplasmsD054219——79——113
Non-small-cell lung carcinomaD002289——77——213
Obstructive lung diseasesD008173——21——811
HypersensitivityD006967EFO_0003785T78.40—4——711
Show 219 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MelanomaD008545——4———26
SclerosisD012598——3———36
Alzheimer diseaseD000544EFO_0000249F032———35
FibromyalgiaD005356EFO_0005687M79.11———45
PharmacokineticsD010599——2———35
Skin neoplasmsD012878EFO_0004198C442———24
Myofascial pain syndromesD009209EFO_1001054—1———34
Amyotrophic lateral sclerosisD000690EFO_0000253G12.212———24
Motor neuron diseaseD016472EFO_0003782G12.22———24
Heart disease risk factorsD000082742——2———24
Show 75 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cognitive dysfunctionD060825—G31.84————77
Healthy dietD000072001——————77
EmergenciesD004630——————66
SarcopeniaD055948EFO_1000653M62.84————66
Chronic diseaseD002908——————55
HypotrichosisD007039——————55
Cerebral palsyD002547—G80————44
Respiratory soundsD012135—R06.1————44
Crohn diseaseD003424EFO_0000384K50————44
Anxiety disordersD001008EFO_0006788F41.1————44
Show 391 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAscorbic acid
INNascorbic acid
Description
L-ascorbic acid is the L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate. It has a role as a coenzyme, a flour treatment agent, a food antioxidant, a plant metabolite, a cofactor, a skin lightening agent, a geroprotector and a food colour retention agent. It is an ascorbic acid and a vitamin C. It is a conjugate acid of a L-ascorbate. It is an enantiomer of a D-ascorbic acid.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=C1O[C@H]([C@@H](O)CO)C(O)=C1O
Identifiers
PDB—
CAS-ID50-81-7
RxCUI—
ChEMBL IDCHEMBL196
ChEBI ID29073
PubChem CID54670067
DrugBankDB00126
UNII IDPQ6CK8PD0R (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
SLC23A2
SLC23A2
Organism
Homo sapiens
Gene name
SLC23A2
Gene synonyms
KIAA0238, NBTL1, SLC23A1, SVCT2, YSPL2
NCBI Gene ID
9962
Protein name
solute carrier family 23 member 2
Protein synonyms
hSVCT2, Na(+)/L-ascorbic acid transporter 2, Nucleobase transporter-like 1 protein, Sodium-dependent vitamin C transporter 2, sodium-dependent vitamin C transporter-2, solute carrier family 23 (ascorbic acid transporter), member 2, solute carrier family 23 (nucleobase transporters), member 1, solute carrier family 23 (nucleobase transporters), member 2, testicular secretory protein Li 48, Yolk sac permease-like molecule 2
Uniprot ID
Q9UP85
Mouse ortholog
Slc23a2 (54338)
solute carrier family 23 member 2 (Q9JM78)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Ascorbic acid
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 125,950 documents
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Safety
Black-box Warning
Black-box warning for: Chromagen, Citranatal, Citranatal 90 dha, Citranatal assure, Citranatal dha, Citranatal essence, Citranatal rx, Enlyte, Ferralet 90, Healthy mamabe well rounded, Hematogen fa, Hematogen forte, Marnatal f, Moms choice rx, Natafort, Nestabs one, Niferex, Pnv prenatal vitamin, Pnv-dha, Pnv-omega, Pr natal 400, Pr natal 400 ec, Pr natal 430, Pr natal 430 ec, Prenata, Prenatal plus multivitamin plus dha minicaps, Prenate dha, Prenate elite, Prenate enhance, Prenate essential, Prenate mini, Prenate pixie, Prenate restore, Primacare, Tristart dha, Vitafol, Vitafol fe plus, Vitafol ob, Vitafol-ob plus dha
Adverse Events
Top Adverse Reactions
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12,008 adverse events reported
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